“Label The Structure Of The Antibody And The Antigen. Variable Region 3. Variable Region 4. Variable Region 2 3 5. Variable Region 6 6. Variable Region 5 SUBMIT RESET 6 AM PROGRESS: 30% Rent Narts Of The Antihody”
Expert Chegg Question Answer:
1. Fab (variable)region: This region is also called as antigen binding region. It has variable sites at the terminal end of heavy chain and light chain. These can bind with varieties of antigens . So this is called antigen binding region.
2.Fc(constant) region: This region is called as constant region as there is no hypervariable factor here. This consists of Heavy chain only. There are no light chain here. This helps in integration of antibody in the plasma membrane of a cell.
3. Disulphide bridge: The bond between two sulphur atoms present here helps in stabilization and connection of light chain and heavy chain. These bonds are abundant in antibodies.
4. Constant region of light chain: The entire light chain is not used as hypervariable region. This region towards the hinge is constant in light chain. This helps in stable structure of antibody.
5. Constant region of heavy chain: This portion of the heavy chain binds with the phospholipid present in the plasma membrane. This part is helpful in attachment of antibody to cell surface.
6.Epitope : This is the portion of the antigen which binds with Fab region of antibody. This is basically a proteinaceous molecule . Its structure has much importance in drug manufacturers, as they are designed to target it many times.
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